DR MANISH-2.pdf laser proctology piles and fistula
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Get the best piles and fistula treatment in Jaipur with advanced laser proctology techniques. Dr. Manish Rajput, a renowned specialist, provides painless, quick, and highly effective treatments for piles, fissures, and fistula. Using cutting-edge laser technology, the procedures ensure minimal discomfort, no stitches, and faster recovery, helping patients return to their daily lives with ease. Dr. Rajput is committed to offering personalized care and long-term solutions, ensuring lasting relief and improved quality of life. With his expertise and modern facilities, you can expect safe and reliable treatment for all proctological conditions.
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EETs regulate blood pressure and vascular homeostasis.
3. Pulmonary Function
Leukotrienes (LTC4, LTD4, LTE4) are potent bronchoconstrictors.
PGE2 has bronchodilatory effects.
4. Renal Function
Prostaglandins regulate glomerular filtration rate and sodium excretion.
EETs contribute to natriuresis.
5. Neurotransmission and Pain
Endocannabinoids modulate pain perception and neuroprotection.
Prostaglandins contribute to central pain sensitization.
6. Reproductive System
P
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Diagnosis involves ultrasound (first-line test), MRCP (for bile duct stones), and ERCP (diagnostic and therapeutic). Laboratory tests like LFTs, CBC, and lipase/amylase help assess complications.
Diet plays a vital role in managing gallstones by reducing gallbladder workload and preventing further stone formation. A low-fat, high-fiber diet is recommended, including lean proteins (fish, tofu), whole grains, vegetables, and healthy fats (olive oil, flaxseeds). High-fat foods, processed foods, red meat, and sugary beverages should be avoided. Adequate hydration (2.5-3 L/day) prevents bile thickening, and small, frequent meals prevent bile stagnation. Gradual weight loss (0.5-1 kg/week) is encouraged, as rapid weight loss can worsen gallstone formation.
A balanced diet with proper weight management and hydration helps reduce symptoms and supports gallbladder health.
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Pharmacoeconomics is a vital field that examines the economic impact of pharmaceutical products and healthcare services. This presentation provides a detailed overview of pharmacoeconomic principles, methodologies, and their significance in healthcare decision-making. It covers essential topics such as cost analysis, evaluation perspectives, and humanistic assessment methods.
💡 Key Topics Covered:
✔ History and Evolution of Pharmacoeconomics
✔ Goals and Objectives of Pharmacoeconomic Studies
✔ Cost Analysis & Consequences (Outcomes)
✔ Different Pharmacoeconomic Methodologies (Cost-Minimization, Cost-Effectiveness, Cost-Utility, Cost-Benefit)
✔ Perspectives in Economic Evaluations (Payer, Patient, Society)
✔ Role of Pharmacoeconomics in Drug Safety & Pharmacovigilance
✔ Humanistic Evaluation Methods (Quality of Life & Patient-Reported Outcomes)
✔ Importance of Pharmacoeconomics in Policy & Healthcare Decisions
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There is no physical contact between two neurones.
Synapse: The point at which the nerve impulse passes from the presynaptic neurone to the postsynaptic neurone.
Presynaptic Neurons: The neurons that carries action potential to the synapse.
Postsynaptic Neurons: Neurons that carries action potential away from the synapse.
Synaptic knobs or terminal boutons: At its free end, the axon of the presynaptic neurone breaks up into minute branches that terminate in small swellings.
These are in close proximity to the dendrites and the cell body of the postsynaptic neurone.
The space between them is the synaptic cleft.
Synaptic knobs contain spherical membrane bound synaptic vesicles, which store a chemical (the neurotransmitter) that is released into the synaptic cleft.
Neurotransmitters are synthesised by nerve cell bodies, actively transported along the axons and stored in the synaptic vesicles.
They are released by exocytosis in response to the action potential in the presynaptic neurons and diffuse across the synaptic cleft.
They act on specific receptor sites on the postsynaptic membrane.
Their action is short lived, because immediately they have acted on the postsynaptic cell such as a muscle fibre, they are either inactivated by enzymes or taken back into the synaptic knob.
Some important drugs act by mimicking, neutralising (antagonising), or prolonging normal actions of neurotransmitters.
Neurotransmitters usually have an excitatory effect on postsynaptic receptors but they are sometimes inhibitory.
There are more than 50 neurotransmitters in the brain and spinal cord including noradrenaline (norepinephrine), adrenaline (epinephrine), dopamine, histamine, serotonin, gamma aminobutyric acid (GABA) and acetylcholine.
Other substances, such as Neuropeptides (enkephalins, endorphins and substance P) have specialised roles in, for example, transmission of pain signals.
Excitatory neurotransmitters: Acetylcholine, Norepinephrine, Dopamine (Initiate New Impulse)
Inhibitory neurotransmitters: GABA, Serotonin, Glycine (Reduces the chance of new impulse, Hyperpolarization).
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Milestone 7 months
At seven months, your baby is becoming more active, curious, and expressive! Many can sit up without support, reach for toys, and even start rocking on their hands and knees, a sign that crawling is coming soon. Their grip is improving, so they enjoy grabbing, shaking, and banging objects together.
Socially, they recognize their name, respond to familiar voices, and may show separation anxiety when a parent leaves the room. They love interactive games like peekaboo and enjoy babbling sounds like “ba-ba” and “da-da.”
Solid foods are now a regular part of their diet, along with breast milk or formula. They may sleep 12–16 hours a day, including two or three naps.
Every baby develops at their own pace, so don’t worry if they’re not hitting every milestone at the same time as others. Enjoy this exciting stage of discovery and growth.
Discover the essential growth and development milestones of a 7-month-old baby. Learn about physical, cognitive, emotional, and social developments, including motor skills, sensory awareness, speech progress, and feeding habits. Get expert parenting tips, activities, and guidance to support your baby's healthy development. Stay informed with this comprehensive guide
Wondering what milestones your 7-month-old should be reaching? This expert guide covers key physical, cognitive, and social developments, from sitting up and babbling to improved
hand-eye coordination. Learn about feeding,
sleep patterns, and fun activities to support your baby's growth. Get top parenting tips and insights to ensure your little one thrives!
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